Dr. Comite began her medical journey at Yale University School of Medicine and continued  at Yale with a residency in Internal Medicine. She completed a clinical and research fellowship in Reproductive Endocrinology (multidisciplinary training incorporating internal  medicine, pediatrics, gynecology, and andrology) at the National Institute of Child Health  and Human Development (NICHD) at the National Institutes of Health (NIH). She remained  at the NIH as a senior clinical research associate before joining the Yale faculty as an  associate professor in three departments—Reproductive Endocrinology in Gynecology,  Internal Medicine, and Pediatrics. During her 25-year faculty tenure, Dr. Comite founded  and directed Women’s Health at Yale in 1992. 

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In 2005, she launched her bespoke medical practice, Comite Center for Precision Medicine & Healthy Longevity, in New York City and, subsequently expanded offices to  Palo Alto and Miami Beach. 

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Dr. Comite has published seminal research in such peer-reviewed journals as New England Journal of Medicine, JAMA, Journal of Endocrinology and Metabolism, among  others. She is a recognized leader in the field of Precision Medicine, utilizing data to  reverse biological aging by incorporating hormone optimization, peptides, and other  targeted interventions personalized for each patient as an Nof1™ with real-world research studies. 

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Dr. Comite’s podcast delivers the truth about your health—that age-related disease begins  early in life at the cellular level. By reversing biological aging, you preserve vitality, extending your healthspan with longevity. Dr. Comite interviews renowned physicians, researchers, and thought leaders offering surprising insights and practical.

Initially trained in internal medicine, Dr Raffaele has been exclusively practicing and researching applied geroscience medicine for 25 years.   He co-founded PhysioAge Medical Group in 1997 where he practiced age management medicine with a focus on personalized hormone optimization and physiological age assessment. In 2007, his co-founded PhysioAge LLC, a web-based health and biomarker analytics data collection and reporting system now used by forward thinking health care practices around the world to assess, monitor, and communicate to patients the effectiveness of their treatments.  Since 2009, he has been involved in clinical telomere biology research and published 4 studies of the effect of oral telomerase activation on the immune system, metabolism, and telomere length in aging adults.  He has lectured nationally and internationally on the clinical application of telomere biology.  In 2015 he founded Raffaele Medical Group and blogs regularly about telomere biology, geroscience research, hormone optimization, and biomarkers of aging on Raffaelemedical.com, @RaffaeleMD, and PhysioAge.com.  He received his B.A. in philosophy from Princeton University and his MD from Drexel University Medical School in 1989. Dr. Raffaele trained at The New York Hospital/Cornell University Medical Center and was formerly a clinical assistant professor of medicine at Dartmouth Medical School while in practice at the Hitchcock Clinic. Dr. Raffaele is a member of the Endocrine Society, is board certified in internal medicine, and is a diplomat of the American Board of Anti-Aging Medicine. 

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Dr. Raffaele, with 25 years of expertise in applied geroscience medicine, co-founded PhysioAge Medical Group in 1997, specializing in personalized hormone optimization and physiological age assessment. In 2007, he established PhysioAge LLC, a global health analytics system. He's conducted research in clinical telomere biology since 2009, publishing 4 studies on oral telomerase activation in aging adults. A renowned lecturer on telomere biology, he founded Raffaele Medical Group in 2015 and blogs on various topics. Dr. Raffaele holds a B.A. in philosophy from Princeton University and an MD from Drexel University Medical School. He trained at The New York Hospital/Cornell University Medical Center and was formerly a clinical assistant professor at Dartmouth Medical School. Dr. Raffaele is an Endocrine Society member, board-certified in internal medicine, and a diplomat of the American Board of Anti-Aging Medicine.

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At 37 years old, Dr. Paul Savage was a successful ER/trauma physician. But he was unhealthy, weighed 270 pounds, smoked cigarettes, was tired, anxious, and unwell, and had high cholesterol, high blood pressure, pre-diabetes, and stress. Rejecting the conventional approach of more medications, his curiosity and determination led him to explore various treatments and lifestyle changes—and transform his life and career through precision medicine. Twenty-five years later, he’s an advocate for combining traditional and integrative medicine, focusing on an evidence-based approach that treats patients as partners.

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Dr. Savage embraces a continuous pursuit of knowledge and integration of the latest medical advancements into his practice, with several board certifications, including certifications from the Stem Cell Fellowship, Integrative Metabolic Medicine, and the American Academy of Anti-Aging Medicine. Not to mention he built over 50 clinics across the United States and literally wrote the code for the industry standard software hat has helped millions of patients.

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Dr. Savage is now the founder and CEO of MDLifespan. His latest endeavor of the patented PlasmaXchangeTM protocol is the culmination of years of expertise — it's poised to be the defining moment of his career, a transformative movement that will reshape the future of medicine as we know it.

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Dr. Jeffrey Gladden, chronologically 70 (Feb 28th 2024), has a mosaic of biological ages ranging as low as his mid-20s, with the majority in his 30s and 40s. Some would call it a miracle, but he calls it Playing the Symphony of Longevity to Live Young for a Lifetime. The Symphony is composed of a truly exponential plan for the exponential problem of aging. We don’t age in a linear way. Aging accelerates exponentially, and virtually all plans that simply focus on eating better, exercise, sleep, stress reduction, hormone replacement, and supplements are a linear strategy to an exponential problem.  From a young age, Jeff saw what aging did to those he loved. At a crucial moment in his life, he can still hear his grandmother telling him, “Jeff, don’t ever get old … it’s hell to get old." Her words were more than a warning, it was a plea for him not to grow old the same way she had.

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As a true trailblazer in Life Energy, Longevity, Health, and Human Performance Optimization Science, Dr. Gladden’s groundbreaking work applies the best science, deepest insights, and the greatest technologies to unlock the secrets to longevity at his clinic, Gladden Longevity.  

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Being a leading cardiologist for over 25 years, Dr. Gladden regularly brought the latest cutting-edge technologies to his patients. During that time, he co-founded the Heart Hospital Baylor Scott & White, was the founder and CEO of a cardiology group with 10 offices and 12 doctors, and created cardiac catheterization labs, rapid response heart attack programs, heart arrhythmia programs, and congestive heart failure programs for outlying communities and hospitals. In addition, he became involved in several medical device startups and, as of this writing, sits on the board of two of them. He discovered that he could always get a better result for his patients by having a deeper understanding of them and the problems they faced enabling him to create precise solutions for them. He brings that same mindset to his work at Gladden Longevity.

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In his early 50s, despite his successes, he started to feel exhausted, was putting on weight, had less energy, when stressed would go become anxious and go over a cliff of depressed, and was developing brain fog. He was struggling to do things that used to be easy.  

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When he went in for medical testing, he was told that “everything checks out ok for your age. You’re just getting older… why don’t we start you on an antidepressant."

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Jeff knew his doctors were not addressing the underlying issues, they were asking the wrong questions, so he went deeper, much deeper, to ask better ones. He extensively trained and got new certifications in functional and age management medicine. His hard work paid off, and after two and half years, he reversed all his symptoms and started feeling better than ever.  

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He then began to wonder, “How good can I be? How fit, how strong, mentally sharp, how spiritually aligned, how relationally replete and for how many years and decades can I carry this forward.”  This empowering question led him to leave the sick care world and focus all his energies on longevity, health, performance, and life energy optimization.  

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“How good can you be?” became the genesis for Gladden Longevity, and he’s never looked back. Having a mindset of only being married to his questions, not his current answers, Dr. Gladden continues to make massive strides in the fields of longevity, health, human performance, and life energy. Gladden Longevity is running IRB-approved trials to safely bring the most cutting-edge technologies to his clients, and he wants to share them with you.

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He released his highly anticipated book, “100 is the New 30: How Playing the Symphony of Longevity Will Enable Us to Live Young for a Lifetime” in September. The book was well-received and quickly became an Amazon bestseller. Dr. Gladden is not only a successful author but also a highly sought-after speaker, providing inspiration around the world through his presentations on the science of longevity.

Dr. Gladden is confident that we can function like a 30-year-old when we are 100. His work and research now include three additional questions:  

How Do We Make 100 The New 30?  

How Do We Live Well Beyond 120?

How Do We Live Young for a Lifetime?  

Today, as the founder of Gladden Longevity, he and his longevity staff create cutting-edge, exponentially impactful, individualized health rejuvenation, performance longevity, and life energy plans.  Each plan is customized to the client, helping them navigate and resolve their issues and teaching them how to play their personal symphony of longevity to maximize their vitality, quality of life, and impact.  

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When he’s not at work, he enjoys his athleticism, artistic, and spiritual sides. He has a super active life: surfing, mountain biking, hiking, snowboarding, playing the guitar, spiritual growth and enlightenment, and spending time with his loved ones. His goal is to follow his trajectory for greatness and make his greatest impact on the planet by having the transcendence and wisdom of a 300-year-old mind in a 30-year-old body. His grandmother is smiling, he’s not growing old, he is growing stronger, mentally sharper, more athletically capable, and spiritually wiser while loving every moment of the journey.

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Dr. De has devoted most of his life to the study of human potential, including a Bachelor’s degree in Biology, Doctorate in Medicine, Master in Business Administration, and a research fellowship in General Surgery and the Metabolic Institute at the Cleveland Clinic. Dr. De and the Biohax medical team are known for contributing advanced studies, research and papers that continue to push the edges of medicine with profound, positive results.

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Dr. De founded Biohax because of his own personal journey where he learned to successfully bio-hack his systems in order to overcome a serious illness. From his personal wellness success, he self-funded and built the Biohax brand.

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Dr. De continues to expand the Biohax brand by doing global speaking engagements and educating the world about topics like epigenetics, human performance, longevity, hormone optimization, heart disease, and more.

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Darshan Shah, MD, is a health and wellness specialist, board-certified surgeon, published author, entrepreneur, and founder of Next Health, the world's first and largest Health Optimization and Longevity clinic. With expertise in all body systems, he has performed over 20,000 surgical procedures, including trauma surgery and complex reconstructive procedures. As a Longevity Medicine specialist, he has advised thousands of patients on how to optimize their well-being and extend their healthspan and lifespan. Dr. Shah began his career at an accelerated MD program and earned his medical degree at the age of 21, becoming one of the youngest doctors in the United States. He continued his training at the Mayo Clinic, one of the most prestigious medical institutes in the country. After earning his board certification, he opened medical/surgical centers throughout California, started four other companies in the Health and Wellness space, and has published a book, authored numerous papers and patented medical devices. Dr. Shah’s belief in continual education and self-improvement has earned him alumni status at Harvard Business School, Singularity University, and other prestigious institutions. His passion is speaking on the topics of longevity and health, having done over 100+ speaking engagements and appearances.

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Pamela Wartian Smith, M.D., MPH, MS spent her first twenty years of practice as an emergency room physician in a level 1 trauma center with the Detroit Medical Center and then 29-years as a Functional/Personalized Medicine specialist. She is an internationally known speaker and author. She also holds a master’s in public health degree along with a master’s degree in Metabolic and Nutritional Medicine. Dr. Smith is in private practice and is the senior partner for The Center For Precision Medicine with offices in Michigan and Florida. She has been featured on CNN, PBS, and many other television networks, has been interviewed in numerous consumer magazines and has hosted two of her own radio shows. Dr. Smith was one of the featured physicians on the PBS series “The Embrace of Aging” as well as the on-line medical series “Awakening from Alzheimer’s” and “Regain Your Brain”. Dr. Pamela Smith is the co- director of the Personalized Medicine Certification at The Morsani College of Medicine, University of South Florida. She is the author of fourteen best-selling books. Her book: What You Must Know About Women’s Hormones, 2 nd edition was released in 2022. Her book, Maximize Your Male Hormones, was released in 2023 and her book What You Must Know About Thyroid Disorders, 2 nd edition, was released late last year. Her newest book, How to Prevent Breast Cancer: Before and After, is due out in January, 2025.

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Dr. Edwin Lee is recipient of the Alan Mintz award, an endocrinologist, author and international speaker. Dr. Lee founded the Institute for Hormonal Balance, Orlando, FL in 2008, is board certified in Internal Medicine, Endocrinology, Diabetes and Metabolism, and has completed special training in Regenerative and Functional Medicine.  He is a graduate of the Medical College of Pennsylvania and finished his 2 fellowships (Critical Care and Endocrinology) at the University of Pittsburgh. He is the author of many books and the latest one is The Fountain of Youth with Peptides. He has published in peer reviewed journals and currently is the assistant professor of Internal Medicine at the University of Central Florida College of Medicine. He has published numerous articles in peer reviewed journals and is passionate in trying to reduce biological age in his patients. Dr. Lee is a co-founder of Clinical Peptide Society and also stated a non-for-profit organization SavePeptides.org to save peptides from the FDA.

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Dr. Vincent C. Giampapa, MD, is a world-renowned medical doctor, inventor, and surgeon specializing in anti-aging medicine. He is one of the first Board Certified anti-aging physicians in the world. He is a co-founder of the American Academy of Anti-Aging Medicine and the first president of the American Board of Anti-Aging Medicine.

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Dr. Giampapa is the founder of the Regenerative Medicine Institute (RMI), located in Costa Rica, and is a visiting scholar at the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School.

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Dr. Giampapa was nominated for a Nobel Prize in both 2014 and 2015 for his groundbreaking research into cellular restoration technology. He also received a Gusi Peace Prize for his work in stem cell reprogramming. He received an Edison Award for developing the first epigenetic nutritional supplement and an A4M Science & Technology Award for developing the BioMarker Matrix Profile -- the first computer program to measure aging. He served as a Nasa consultant for the space shuttle robotic arm and has been awarded 24 patents from the United States Government for unique cell culture delivery techniques, stem cell reprogramming, new drug delivery systems, and surgical instrument designs.

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Dr. Giampapa is the author of five books on health and longevity and the first medical textbook on Anti-Aging Medicine and Age Management. Based on 34 years of surgical experience and 25 years of research, Dr. Giampapa is passionate about extending healthy life spans with enhanced functions. He views the global aging dilemma as one of the critical challenges for humanity in the next decade. His research focuses on stem cells and our body's innate ability to regenerate and maintain a longer and healthier life span.

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Dr. Sanjeev Goel is the lead physician at Kennedy Medical Centre (KMC) for past 20+ years as well founder and CEO of Peak Human, an anti-aging and regenerative medicine practice.

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He is passionate about a holistic approach to wellness and has done training in Anti-Aging, Integrative and Regenerative Medicine. He advocates a healthy lifestyle centred around a plant based diet, focused physical activity and enhancing mental resilience.

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Sanjeev is the host of the Peak Human Podcast (found both on the Apple and Google Platforms), where he discusses biohacking and regenerative medicine with guests on a weekly basis.

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Dr. Helen Messier has dedicated most of her career to harnessing data to bridge the  translational gap in medicine. She has cultivated a unique expertise in seamlessly  integrating multi-omic data and digital health technologies into real-world clinical care, to  enable patients to realize the beneficial potential of biomedical technologies. 

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Dr. Messier holds a Bachelor of Science with Honors in Genetics and a Ph.D. in Molecular Immunology from the University of Alberta. Following her doctoral studies,  she completed post-doctoral studies at the La Jolla Institute for Allergy and Immunology  in San Diego, CA, and received her MD from the University of Calgary. She is certified  in family medicine. 

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Beyond clinical practice, Dr. Messier has left an indelible mark as a notable innovator  and healthcare entrepreneur. Alongside her roles on various medical and scientific  advisory boards, she founded a national network of concierge medical practices in  Canada, served as the Medical Director of Genomics at Human Longevity Inc, and  played a pivotal role as the inaugural Chief Medical Officer of Viome. 

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In her current role as the Chief Medical and Science Officer at Fountain Life, Dr.  Messier is delighted to bring her extensive experience and profound knowledge to  further advance her mission in expanding proactive and preventative medicine. In  addition to leading the company’s clinical and scientific programs, Dr Messier is  establishing Fountain Life University, to train Fountain Life certified practitioners and  lead the effort to gain insights and publish findings from Fountain Life’s vast amount of data.

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