What is Your Biological Age?
Everyone knows their chronological age.
Chronological age is the number of candles that are on top of your cake and the birthdays you celebrate (or sometimes don’t!). However, developments in science have created another measurement of age called biologic age.
This measurement of age is based on years of statistical research which can predict how healthy you are and how long you might live.
The novel DNA biomarker uses markers on your DNA called methylation (DNA methylation means the changes in your DNA due to outside factors) to predict your age.
Your biological age is more accurate at predicting health span (how healthy you are) and lifespan (how long you will live) than any previous molecular biomarker, and can be correlated to age-related conditions such as Alzheimer’s disease and cancer.
Ideally, everyone would want their biological age to be less than their chronological age.
This means that you are living a lifestyle that is healthy and will help decrease the risk of sickness and chronic diseases.
It is a single metric that takes all the important health data (weight, sex, cholesterol level, exercise frequency, etc.) about an individual and is able to report back how healthy you are… If you could reverse your risk of age-related disease and avoid sickness, wouldn’t you want to know how?
Why is your Biological Age so Important?
When we are born, all of our cells have the same DNA.
The cells in your eyes have the same DNA as the cells in your hair. So what makes them different?
The answer is each cell chooses to turn on some genes and turn others off. For example, your eyes express different genes than your hair.
This is called expression and it is controlled by the markers we measure with our TruAge testing kit.
Unfortunately, as we age, natural DNA expression can become much harder to regulate. The genes which should be expressed in your eyes aren’t regulated as well and you start to lose function.
Therefore, you see a degradation in vision as you age. In fact, aging is defined as the progressive loss of function as you age. So what does this have to do with biological age measured by TruAge?
TruAge can report how old your cells and DNA look. This means that you can measure how likely you are to develop a specific disease or even, how long you might live!
Often, knowing how to be the healthiest you can be is difficult. Doctors measure blood levels like cholesterol, inflammation, and blood sugar. They perform tests such as colonoscopies, vision tests, and physical function tests. Now, with this single measurement, you can link your health and longevity to a single, simple test which can help you and your doctor know the best way to address your health concerns in the most personalized and effective way!
Other Applications of TruAge™
How your DNA is methylated isn’t just a predictor of age, it is also a predictor of many other diseases and health statuses. For instance, how much a person exercises can change their biological age and the methylation of their DNA. In fact, certain methylation changes have been directly correlated to all of the following:
- Huntington’s disease
- Coronary artery disease
- Estimator telomere length
- Heart attack risk
- Risk of cardiovascular disease
- Education, race, ethnicity
- Replicative senescence (Rapamycin)
- Hypoxia (Donor age)
- Developmental timing
- Maternal sleep loss
- Lifespan and healthspan
- Inflammation and chronic disease
- HIV and neurocognitive disorders
- Metabolic disease
- Lung function
- Pubertal development
- Blood pressure
- Brain aging
- T cell composition
- Heroin users
- Wener syndrome
- Diet and exercise
- Rheumatoid arthritis
- Developmental maturity
- Lung cancer
- Psoriatic skin lesions
- Downs syndrome
- Stress and PTSD
- Alzhiemers amyloid plaques
- Breast cancer
TruAge is just the beginning of diagnostic predictors of disease but it is one that is linked to all outcomes. By providing more data about your health history to our research team we are able to develop tests to predict risks but also see which interventions most reduce this risk of our patients.
If you reduced the incidence of aging by 7 years you could cut the incidence of disease in half. Imagine what this means for us, our family members, our friends, and the world! But we need your help to do it.