A case study on clock limitations through the lens of DunedinPACE algorithm.
Aging is cellular loss of function.
In longevity research, we track molecular markers that have been correlated with that aging process. While your chronological age will always progress at a fixed rate, biological age can show a summary of how a person’s lifestyle choices and behaviors are affecting their body.
We don’t all age in the same way, at the same rate.
Accelerated Aging is the #1 risk factor for most major chronic diseases.
With TruAge PACE, you can measure your epigenetic age acceleration, and use our reports as a reference point to begin tracking how your lifestyle changes are affecting your aging at a molecular level.
We measure aging, so you can more effectively manage it.
TruAge PACE is a biological pace of aging test that focuses on short-term changes in methylation that translate into long-term impacts to health. It acts like a speedometer for aging, where values above 1 are 'accelerated aging' and below 1 are 'slowed aging.'
The primary algorithm offered in PACE is the Dunedin Pace of Aging algorithm (DunedinPACE) - developed over 50 years and trained on longitudinal phenotypic data. Dr. Eileen Crimmons in USC evaluated DunedinPACE, and found it was the most predicative age-related biomarker for health consequences.
Because of the high precision, and significance of small changes, you can retest frequently. Watch your rate of aging change in response to lifestyle changes, and figure out what changes work best for you.
We recommend 3 months between tests.
Of all aging clocks, DunedinPACE offers the highest ICC value, across the board. It is the most reliably consistant and reproducable.
|What's Included?||TruAge Complete Collection||TruAge PACE|
|Epigenetic Biological Age | Your whole-body summary||✓||no|
|Telomere Length | Aging based on cellular replication||✓||✓|
|Dunedin PACE | A speedometer for pace of aging||✓||✓|
|Extrinsic Epigenetic Age | Immune System Impact on Age||✓||no|
|Intrinsic Epigenetic Age | Aging Independent of Immune System||✓||no|
|Immune cell-type ratios and CD4:CD8 ratio||✓||no|
|Weight Loss Response to Caloric Restriction||✓||no|
|Download CpG beta values | Your raw epigenetic data||✓||no|
|Lifetime Guarantee: new trait reports added as they’re discovered.||✓||no|
|Lifestyle suggestions sourced to the latest public research on epigenetic aging||✓||✓|
|Access advanced metrics and health insights with our free consult.||✓||no|